Angelo picks Max Holloway, but with low confidence. He notes that Dustin is the better all-around fighter but may be pressured by his retirement fight and home crowd, leading him to brawl instead of using his full skillset. He expects Holloway's volume striking to win a decision. He will not bet on this fight.

Big Brady leans Max Holloway, citing Holloway's improvement at lightweight and youth (33 vs 36). He worries about Holloway's chin after his first KO but believes Holloway's volume will be key. He notes Poirier's retirement and hometown advantage could sway a close decision, so he's not betting.

Connor believes Holloway has evolved into a more complete striker since their last fight, with improved footwork, counterpunching, and kicking game. He thinks Holloway was close to winning the second fight and that his cleaner combinations and pressure can overcome Poirier's power if he survives the turning points. He also notes Poirier's retirement talk as a potential factor that could affect his focus.

The host notes Poirier is up 2-0 in the series and believes his power punching approach will be more effective than Holloway's volume, referencing the second matchup where Poirier won 4-1 on scorecards. He expects Poirier to repeat that and win on the scorecards.

The MMA Guru picks Max Holloway over Dustin Poirier, predicting a decision win. He cites Holloway's superior striking and the fact that Poirier is retiring after this fight, which may affect his intensity. The Guru also notes that Holloway nearly won their second fight and is now properly prepared at lightweight, unlike the short-notice rematch. He believes Poirier's striking has regressed due to focusing on takedown defense, while Holloway's striking remains sharp. He expects a competitive fight but sees Holloway as a step ahead.

Angelo picks Islam Makhachev confidently, citing his superior wrestling and pressure. He believes Islam will get takedowns at will and potentially finish Dustin Poirier. He acknowledges Poirier's toughness and one-punch power but thinks the grappling gap is too wide. He mentions a fantasy scenario where Poirier wins by submission but calls it highly unlikely.

Big Brady is heavily on Islam Makhachev, calling him his favorite play on the board and planning 100% exposure. He expects Islam to get takedowns and finish in the second or third round. He acknowledges Dustin Poirier's power and cheap price but sees a very limited path for Poirier. He will sprinkle a little on Poirier but is confident Islam gets the job done inside the distance.

Cody agrees Makhachev is the favorite but notes Poirier's puncher's chance and the appealing +500 underdog price. He discusses Poirier's win over Benoît Saint Denis, which he considers tainted due to Saint Denis having a staph infection. Cody believes Makhachev will take Poirier down and grind him out, likely submitting him late or winning by TKO. He also likes the over 2.5 rounds at +145.

Daniel acknowledges Islam's dominant grappling and improved striking, noting his win over Volkanovski. He points out that Dustin has faced grapplers like Khabib and Oliveira, but the Dagestani style is uniquely relentless. He mentions the possibility of Poirier landing a check hook like Martins did, but ultimately sees Islam's path to victory as more likely. He is rooting for Poirier but picks Islam as a pure pick.

Daniel Vreeland picks Makhachev but disagrees that he's a better striker than Poirier. He notes Makhachev's striking is overrated based on the Volkanovski fight. However, he believes Poirier will give up too many positions and won't be on his feet long enough to win a decision. Vreeland thinks Poirier's only path is a finish, but Makhachev is durable and has gone 25 minutes with Volkanovski. He suggests Poirier's props (KO or submission) are better value than his moneyline.

Jeff Fox picks Makhachev, calling him 'Khabib with hands.' He believes Poirier has no advantage anywhere, especially now that Makhachev is knocking people out on the feet. Fox sees no realm where Poirier is better and expects Makhachev to dominate.

The host expects Makhachev to take the fight to the ground and submit Poirier, similar to how Khabib and Oliveira did. Poirier's grappling defense has been exploited by elite wrestlers, and Makhachev's pressure and top control should lead to a rear-naked choke. The host sees this as an easy win for Makhachev and likes the submission prop.

Paul picks Makhachev to win, noting Poirier's age (35) and the historical stat that fighters over 35 under 155 lbs are 0-15 in title fights. He believes Makhachev's takedowns will be there whenever he wants, but warns that Makhachev has had bad performances before (like against Adriano Martins and Volkanovski) and could get into trouble if he stands with Poirier. He suggests betting the over 1.5 or over 2.5 rounds instead of the moneyline at -700.

Angelo picks Benoît Saint Denis, citing his pressure, power, and wrestling. He worries that Dustin Poirier's chin may have deteriorated after the Justin Gaethje knockout. He thinks Saint Denis can overwhelm Poirier early. However, he won't bet because he's rooting for Poirier.

Big Brady picks Benoît Saint Denis to win by second-round submission. He notes that Saint Denis is younger, hungrier, and has grappling upside. He believes Saint Denis will get Poirier down and submit him, similar to how Michael Chandler did. He acknowledges Poirier's striking advantage but thinks Saint Denis's durability and pressure will be too much.

Cody points to Poirier's declining volume and durability, noting he has been outstruck in recent fights and is showing signs of wear. He contrasts that with Saint Denis's relentless pressure, cardio, durability, and progression. He believes Saint Denis will break Poirier's will as the fight goes on.

Daniel picks Poirier but is very hesitant due to Poirier's age and coming off a head kick KO loss. He acknowledges Poirier is the more skilled striker and believes he can knock out Saint Denis on the feet. However, he worries about Saint Denis's pressure, grappling, and durability, and whether Poirier still has the will and cardio to go five rounds. Daniel notes that if Poirier drops Saint Denis, he might follow him to the ground unlike against Charles Oliveira. He ultimately leans on Poirier's skill advantage.

Daniel Vreeland picks Benoît Saint Denis but expresses discomfort with the -205 price. He believes BSD's wrestling and pace will be too much for Poirier, especially given Poirier's recent knockout loss. Vreeland notes that BSD has finished all his opponents and has never been finished. However, he calls the line a 'dog or pass' spot because BSD has never fought anyone as tough as Poirier. He says he would rather see BSD fight someone like Rafael Fiziev before this step up. Despite the price, he picks BSD because he has never picked against him.

Jeff Fox picks Benoît Saint Denis as well, noting that he has never picked against BSD and won't start now. He acknowledges the massive step up in competition from Matt Frevola to Dustin Poirier, but believes BSD's wrestling and finishing ability are real. Fox points out that Poirier has been knocked out recently and that BSD has the power to put him away. He also mentions that BSD is younger and has a relentless pace. However, he says he won't bet real money on this fight due to the price and the step up.

Saint Denis is a relentless pressure fighter with five straight finishes. He uses leg kicks, body work, and clinch pressure to break opponents, then works to the back for rear-naked chokes. Poirier is a better striker but struggles against aggressive grapplers who can close the distance, as seen in losses to Khabib and Oliveira. Poirier does not want this fight and may be mentally checked out. I expect Saint Denis to break Poirier within the first two rounds and secure a submission.

Paul emphasizes Poirier's mileage and the fact that he didn't even know the fight was on until recently, suggesting he hasn't been sparring hard. He contrasts that with Saint Denis's hunger and youth, and notes that Saint Denis has never been finished and has shown incredible durability and pace.

Angelo picks Dustin Poirier, expecting a similar fight to their first meeting but without a finish. He believes Poirier's technical striking and fight IQ will outpoint Gaethje over five rounds. He notes that both have evolved at the same pace, but if Gaethje uses wrestling, it could change things. He is excited for the fight but not betting on it.

Big Brady picks Dustin Poirier to win by late third-round finish. He references the first fight where Poirier landed 142 head strikes and broke Gaethje in the fourth round. He trusts Poirier's durability (only two KO losses in 36 fights) and volume, and expects damage to accumulate. However, he is not confident, acknowledging Gaethje's improvements and power. He calls it a toss-up but leans Poirier.

Cody picks Poirier based on the first fight where Poirier adjusted after leg kicks and knocked Gaethje out. He notes Poirier's training partners at ATT (Chris Duncan, Grant Dawson) have had career-best performances recently, suggesting good camp. He acknowledges Gaethje's leg kicks and durability but believes Poirier's boxing and ability to weather the storm give him the edge. He does not plan to bet pre-fight.

James picks Poirier, trusting his boxing accuracy, durability in wars, and ability to adjust to leg kicks. He notes Gaethje has improved technically but still gets hit and has been finished in wars before. He expects a war that goes into championship rounds, with Poirier's dog and cardio giving him the edge.

Poirier's precision striking and combinations will hurt Gaethje eventually and put him away. The fight doesn't go to decision is the spot I lean into most. Poirier by knockout, probably in the fourth or fifth round. Gaethje's leg kicks were effective in the first fight but Poirier's hands will find the big shot again.

Angelo acknowledges Chandler's power and wrestling but does not trust him to fight to win rather than slug it out. He believes Poirier is the smarter, more composed fighter focused on winning a title. He picks Poirier because Chandler cannot be trusted to try to win, though he expects an exciting fight.

Big Brady picks Dustin Poirier to win by knockout in the second round. He believes Poirier is the better technical striker with better cardio, and that Chandler's chin is questionable after taking damage. He compares it to Chandler's fight with Gaethje, but notes Poirier has more power and better cardio. He expects a stand-up war with no takedowns, and that Chandler will slow down as the fight goes on.

Cody picks Michael Chandler as a plus money underdog, expecting chaos in the fight. He notes that both fighters will eat massive shots and that Chandler has a legitimate chance on any given night due to his athleticism, wrestling, and power. Cody believes Chandler's willingness to throw down and his durability make him live at the plus price, and he sees the fight as a 50/50 proposition.

Daniel Levi picks Dustin Poirier to knock out Michael Chandler, citing Poirier's volume, knockout power, and finishing ability when he smells blood. He notes that Chandler is susceptible to calf kicks and tends to get wild, which could lead to a straight left from Poirier. Levi respects Chandler's explosiveness and D1 wrestling but believes Poirier's experience and the 'Poirier Blitz' will be the difference. He mentions that he wanted to bet Poirier but missed the line at -175, so he is passing on a bet. He also discusses the danger of Chandler's one-punch power and the potential for a first-round knockout from either side.

The host sees Poirier as the better technical striker and believes his discipline will keep him out of trouble. He acknowledges Chandler's power and speed but thinks Poirier will outbox him and potentially get a late KO. He notes the line at -210 is a bit wide but still picks Poirier. He expects knockdowns and a possible finish from Poirier.

Paul picks Dustin Poirier by TKO, believing Poirier's boxing combinations and durability will be the difference. He notes that Chandler has durability issues and has been knocked out before, and that Poirier's pressure and volume will break Chandler down. Paul also mentions that Poirier is highly motivated and looks good in training, and that Chandler's recklessness could lead to him getting caught. He prefers the Poirier by TKO prop at plus money.

Big Brady picks Charles Oliveira to win by submission in the second round, but with low confidence. He notes that Oliveira has improved immensely, answering questions about his cardio and chin. He believes Oliveira can get the fight to the mat, where he is a wizard, and submit Poirier. Poirier has the striking advantage and good takedown defense, but has been taken down by grapplers like Dan Hooker. Brady is staying away from moneyline bets and is playing props.

Daniel Levi picks Dustin Poirier to win the lightweight title. He emphasizes Poirier's finishing instinct, particularly his patented blitz when he hurts opponents, and his ability to throw high volume (350+ strikes in recent fights). Levi notes that Poirier has survived deep submission attempts before, unlike Michael Chandler who made a 'meathead error' against Oliveira. He believes Poirier's composure and experience on big stages will be key, and that he will hurt Oliveira standing and finish him without making a mistake.

This is a volatile fight. Poirier is the slightly better boxer and should weather Oliveira's early aggression. Oliveira's striking has improved, but Poirier's defensive soundness and experience in five-round fights give him an edge. The fight likely ends inside the distance, and Poirier's finishing ability in later rounds is key. The 'fight doesn't go to decision' is a strong play.

Angelo flips his pick from the last fight, now favoring Conor. He notes that in the first fight, Conor landed everything with power and had Dustin in trouble multiple times, but didn't capitalize due to pacing. He believes Conor will have a plan for the leg kicks this time and will get the job done. He also placed a bet on Conor by KO/TKO for plus odds.

Big Brady picks Conor McGregor to win by first-round knockout. He notes that Conor has the X-factor power, being the hardest hitter pound-for-pound, and that Poirier absorbs a lot of strikes (4.17 per minute). He expects Conor to make adjustments, stuff takedowns, check leg kicks, and keep the fight at range. He acknowledges Poirier's durability but believes Conor will land a knockout.

Cody picks Poirier based on Conor's fading cardio after the first round, Poirier's durability and leg kicks, and the American Top Team camp. He notes Conor's power early but expects Poirier to take over late. He hasn't bet yet, waiting to see how the press conferences affect Poirier's mindset.

Daniel Levi picks Dustin Poirier to win the trilogy. He emphasizes Poirier's superior cardio, output, and durability, noting that Poirier has the most knockouts in UFC lightweight history and has shown he can overcome adversity. He points out that since 2016, Poirier is 7-1 while McGregor is 1-3, and that McGregor struggles in deep waters and has diminishing durability. He predicts a submission win for Poirier, citing the check right hook, calf kicks, takedowns, and clinch work as key factors.

Jacob initially favored Dustin but switched to Conor after rewatching the first fight. He notes Conor landed everything in round one but paced himself too much. He thinks Conor will blitz early to avoid calf kicks and finish in the first round. He also mentions a possible staph infection on Conor's elbow, which could affect cardio and push Conor to an early finish.

I'm going with Poirier here, but I have no real confidence. I think Poirier's durability and cardio have improved at 155, and he can eat McGregor's shots now. McGregor might have a new game plan, but I expect Poirier to take over in the later rounds and finish him, probably in the third or fourth round. I'm not betting this fight myself, but I like Poirier inside the distance and the fight not going to decision.

Paul picks Poirier, citing Conor's durability issues and long layoffs. He notes Conor's power early but believes Poirier's durability and cardio will prevail. He mentions the distraction of Conor's trash talk and the Colby Covington sparring video, but still favors Poirier.

Big Brady picks Conor McGregor to win by first-round knockout, similar to their first fight. He notes McGregor's power and accuracy as key advantages, and believes Poirier's cardio won't be a factor because the fight won't go deep. He acknowledges Poirier could be a live dog but ultimately sides with McGregor's striking superiority.

Daniel Levi picks Conor McGregor to win early, citing McGregor's devastating power and ability to finish fights in the first round. He acknowledges Poirier's improved chin at lightweight and his path to victory if he survives the early storm, but believes McGregor's power is too much. Levi expresses personal rooting interest for Poirier but makes a logical pick for McGregor.

McGregor has the precision and power to replicate his first-round knockout from their first fight. Poirier is durable but has been knocked down by lesser power. McGregor's takedown defense is solid, and he should be able to keep the fight on the feet. Poirier's cardio advantage may not matter if McGregor lands early. I see McGregor winning by first-round KO.